SCHEMBL5598181

SCHEMBL5598181

CCO[Si](OCC)(OCC)C(C)(C)OCC1CO1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
TSHR P16473 4/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
PPARG P37231 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598307 0.86 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL8355397 0.85 ALDH1A1 (0.53) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598560 0.83 SMN1; SMN2 (0.51) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598382 0.82 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598359 0.81 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5598453 0.80 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5370012 0.75 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL8346925 0.73 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL5360156 0.73 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL8418409 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10266707-B2 Scratch and abrasion resistant UV blocking glass coating TRU VUE, INC. (US) 2019-04-23 US disclosed
US-20160340523-A1 SCRATCH AND ABRASION RESISTANT UV BLOCKING GLASS COATING TRU VUE, INC. 2016-11-24 US disclosed
EP-3002263-A1 SCRATCH AND ABRASION RESISTANT UV BLOCKING GLASS COATING Tru Vue, Inc. (US) 2016-04-06 EP disclosed
EP-1764398-B1 Hard coat composiiton and optical element ITOH OPTICAL IND (JP) 2015-07-22 EP disclosed
US-20140363683-A1 SCRATCH AND ABRASION RESISTANT UV BLOCKING GLASS COATING TRU VUE, INC. 2014-12-11 US disclosed
EP-1764398-A1 Hard coat composiiton and optical element Itoh Optical Industrial Co., Ltd. (JP) 2007-03-21 EP disclosed
EP-1273639-B1 OPTICAL ELEMENT ITOH OPTICAL IND (JP) 2006-10-25 EP disclosed
EP-1273639-A1 OPTICAL ELEMENT Itoh Optical Industrial Co., Ltd. (JP) 2003-01-08 EP disclosed
US-5986124-A Method for making compounds containing hydrocarbonoxysilyi groups by hydrosilylation using hydrido (hydrocarbonoxy) silane compounds DOW CORNING ASIA, LTD. (JP) 1999-11-16 US disclosed