Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598181 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8346925 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL28127235 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5598307 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5598382 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5370012 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5598359 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5360156 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5598560 | 0.73 | SMN1; SMN2 (0.51) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL5598453 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986124-A | Method for making compounds containing hydrocarbonoxysilyi groups by hydrosilylation using hydrido (hydrocarbonoxy) silane compounds | DOW CORNING ASIA, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |