Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | F12 | P00748 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | NOS3 | P29474 | 1/20 | 0.59 |
| ▸ | NOS1 | P29475 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7002084 | 0.98 | PLAU (0.57) | PLAUF12NCF1NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL5729154 | 0.98 | PLAU (0.57) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL3816448 | 0.84 | PLAU (0.53) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL29358323 | 0.82 | CNR2 (0.53) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL111310 | 0.82 | CNR2 (0.53) | PLAUF12NCF1NOS3NOS1 | |
| Naphthalene SCHEMBL10758679 | 0.81 | CNR2 (0.51) | PLAUF12NCF1NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL4433615 | 0.81 | CNR2 (0.51) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL28198741 | 0.81 | CNR2 (0.51) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL25482213 | 0.80 | CYP2A6 (0.53) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL6448849 | 0.79 | PLAU (0.48) | PLAUF12NCF1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072041-A1 | THERAPEUTIC COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |