Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | NCF1 | P14598 | 1/20 | 0.52 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358323 | 1.00 | CNR2 (0.53) | CNR2PLAUF12NCF1NOS3 | |
| SCHEMBL28198741 | 0.98 | CNR2 (0.51) | CNR2PLAUF12NCF1NOS3 | |
| Naphthalene SCHEMBL10758679 | 0.98 | CNR2 (0.51) | CNR2PLAUF12NCF1NOS3 | |
| Hydrochloric Acid SCHEMBL4433615 | 0.98 | CNR2 (0.51) | CNR2PLAUF12NCF1NOS3 | |
| SCHEMBL27503462 | 0.93 | CNR2 (0.51) | CNR2PLAUF12NCF1NOS3 | |
| SCHEMBL4279451 | 0.93 | RAB9A (0.50) | CNR2PLAUF12NCF1NOS3 | |
| Hydrochloric Acid SCHEMBL4282133 | 0.92 | RAB9A (0.49) | CNR2PLAUF12NCF1NOS3 | |
| Trifluoroacetic Acid SCHEMBL5484985 | 0.90 | CNR2 (0.56) | CNR2PLAUF12NCF1NOS3 | |
| SCHEMBL4404077 | 0.84 | CNR2 (0.64) | CNR2PLAUF12NCF1NOS3 | |
| SCHEMBL5357601 | 0.82 | CNR2 (0.54) | CNR2PLAUF12NCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004797-A | Preparation method and application of isoquinolyl amide compound | 湖南科技大学 | 2025-05-16 | — | — | CN | claimed |
| EP-3386511-B2 | METHODS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-03-20 | — | — | EP | claimed |
| EP-4126843-A1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | Bristol-Myers Squibb Company (US) | 2023-02-08 | — | — | EP | claimed |
| CN-114404413-A | Compositions and methods for treating anemia | 阿克比治疗有限公司 | 2022-04-29 | — | — | CN | claimed |
| WO-2021194914-A1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-09-30 | — | — | WO | claimed |
| CN-113072496-A | Preparation method of isoquinoline-1-formamide compound | 湖北工业大学 | 2021-07-06 | — | — | CN | claimed |
| CN-110248933-A | Novel quinoline and isoquinoline derivatives for the treatment of pain and pain related disorders | 埃斯特韦制药股份公司 | 2019-09-17 | — | — | CN | claimed |
| CN-107151245-B | A kind of preparation method of levo-praziquantel | 苏州同力生物医药有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108697709-A | Methods for treating huntington's disease | PTC医疗公司 | 2018-10-23 | — | — | CN | claimed |
| WO-2018081202-A1 | MARKERS OF CHRONIC FATIGUE SYNDROME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-03 | — | — | WO | claimed |
| EP-1140106-A1 | TREATMENT OF DISEASES INVOLVING CYST FORMATION | SCIOS INC. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000076505-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |
| EP-1042291-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | claimed |
| WO-2000037085-A1 | TREATMENT OF DISEASES INVOLVING CYST FORMATION | SCIOS INC. (US) | 2000-06-29 | — | — | WO | claimed |
| WO-2000037086-A1 | AGONISTS AND ANTAGONISTS OF PERIPHERAL-TYPE BENZODIAZEPINE RECEPTORS | SCIOS INC. (US) | 2000-06-29 | — | — | WO | claimed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| WO-2000035883-A1 | CONTINUOUS PROCESS FOR THE PREPARATION OF OPTICALLY PURE DECAHYDROISOQUINOLINECARBOXAMIDE | SK CORPORATION (KR) | 2000-06-22 | — | — | WO | claimed |
| WO-1999031064-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| EP-0620820-A1 | NOVEL SUBSTITUTED OXAZINOISOQUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1994-10-26 | — | — | EP | claimed |
| WO-1993012118-A1 | NOVEL SUBSTITUTED OXAZINOISOQUINOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-06-24 | — | — | WO | claimed |