Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111310 | 0.98 | CNR2 (0.53) | CNR2PLAURAB9APLGF12 | |
| SCHEMBL29358323 | 0.98 | CNR2 (0.53) | CNR2PLAURAB9APLGF12 | |
| SCHEMBL28198741 | 0.96 | CNR2 (0.51) | CNR2PLAURAB9APLGF12 | |
| Hydrochloric Acid SCHEMBL4433615 | 0.96 | CNR2 (0.51) | CNR2PLAURAB9APLGF12 | |
| SCHEMBL27503462 | 0.91 | CNR2 (0.51) | CNR2PLAURAB9APLGF12 | |
| SCHEMBL4279451 | 0.91 | RAB9A (0.50) | CNR2PLAURAB9APLGF12 | |
| Hydrochloric Acid SCHEMBL4282133 | 0.90 | RAB9A (0.49) | CNR2PLAURAB9APLGF12 | |
| Trifluoroacetic Acid SCHEMBL5484985 | 0.89 | CNR2 (0.56) | CNR2PLAURAB9APLGF12 | |
| SCHEMBL4404077 | 0.82 | CNR2 (0.64) | CNR2PLAURAB9APLGF12 | |
| SCHEMBL5357601 | 0.81 | CNR2 (0.54) | CNR2PLAURAB9APLGF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711890-A | TREATMENT OF ANXIETY STATES OR OF PULMONARY, RENAL, CIRCULATORY OF CARDIOVASCULAR DISORDERS | RHONE-POULENC SANTE (FR) | 1987-12-08 | — | — | US | disclosed |
| US-4684652-A | TREATING ANXIETY OR CARDIOVASCULAR DISORDERS | RHONE-POULENC SANTE (FR) | 1987-08-04 | — | — | US | disclosed |