Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.52 |
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703748 | 0.91 | TSHR (0.61) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| SCHEMBL439710 | 0.91 | TSHR (0.61) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| Hydrochloric Acid SCHEMBL155429 | 0.90 | KIF11 (0.59) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| Hydrochloric Acid SCHEMBL155430 | 0.90 | KIF11 (0.59) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| SCHEMBL29203888 | 0.90 | KIF11 (0.59) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| SCHEMBL30865102 | 0.90 | KIF11 (0.59) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| Sulfuric Acid SCHEMBL28225219 | 0.89 | KIF11 (0.52) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| Ethylene SCHEMBL28103381 | 0.88 | KIF11 (0.58) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| Nitrogen SCHEMBL8136806 | 0.88 | KIF11 (0.58) | KIF11HSP90AA1CXCR5APLNRCCR6 | |
| Methyl Alcohol SCHEMBL7379508 | 0.86 | PTPRC (0.58) | KIF11HSP90AA1CXCR5APLNRCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| CN-103492028-B | Sulfonaminoquinoline hepcidin antagonists | 维福（国际）股份公司 | 2017-02-08 | — | — | CN | disclosed |
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | disclosed |
| CN-103492028-A | Novel sulfonaminoquinoline hepcidin antagonists | VIFOR INT AG | 2014-01-01 | — | — | CN | disclosed |
| CN-100351243-C | Peptide nucleic acid oligomers from 1-benzenesulfonyl-3-amino acid side chain-4- (2-nucleobase acetyl) -piperazin-2-one | PANAGENE INC (KR) | 2007-11-28 | — | — | CN | disclosed |
| EP-1815860-A2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1465638-B1 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORP (US) | 2007-05-16 | — | — | EP | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-7119120-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2006-10-10 | — | — | US | disclosed |
| CN-1745087-A | Novel tricyclic azepine derivatives, method for production therof and pharmaceutical compositions comprising the same | SERVIER LAB (FR) | 2006-03-08 | — | — | CN | disclosed |
| EP-1465638-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2004052313-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040019113-A1 | Phosphate transport inhibitors | GELTEX PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| CN-1438998-A | Quinolinyl and benzothiazolyl PPAR-gamma modulators | TULARIK INC (US) | 2003-08-27 | — | — | CN | disclosed |
| WO-2003057225-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1295677-A | Method and apparatus for accelerated orthokeratology | EASTA PHARMACEUTICALS INC (US) | 2001-05-16 | — | — | CN | disclosed |
| CN-1281451-A | Benzamidine derivatives | MERCK PATENT GMBH (DE) | 2001-01-24 | — | — | CN | disclosed |
| CN-1260345-A | Hydrazide compound, its preparing method and medicine compositions thereof | ADIR ET COMPANGIE (FR) | 2000-07-19 | — | — | CN | disclosed |
| CN-1215990-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-05-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019113-A1 | Phosphate transport inhibitors | SLC34A1, SLC34A2, SLC20A1 | KIF11 4782/4885HSP90AA1 3241/4885CXCR5 4273/4885 |
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | KIF11 4700/4885HSP90AA1 2743/4885CXCR5 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.