Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18642986 | 0.81 | PTK2 (0.46) | L3MBTL1KDM4ELMNACYP1A2PANK3 | |
| SCHEMBL14840510 | 0.78 | GRM5 (0.46) | L3MBTL1ADORA1NPC1RAB9APOLB | |
| SCHEMBL18642987 | 0.77 | ADORA2A (0.43) | KDM4EADORA1NPC1RAB9AALDH1A1 | |
| SCHEMBL18643148 | 0.77 | HSD17B10 (0.42) | ADORA1NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL856063 | 0.76 | MEN1 (0.53) | L3MBTL1KDM4EKDRNPC1RAB9A | |
| SCHEMBL3922902 | 0.76 | L3MBTL1 (0.48) | L3MBTL1KDM4EADORA1NPC1RAB9A | |
| SCHEMBL15017984 | 0.75 | L3MBTL1 (0.47) | L3MBTL1KDM4EADORA1KDRNPC1 | |
| SCHEMBL5591663 | 0.75 | L3MBTL1 (0.47) | L3MBTL1ADORA1KDRNPC1RAB9A | |
| SCHEMBL17857141 | 0.75 | L3MBTL1 (0.47) | L3MBTL1KDM4EADORA1KDRNPC1 | |
| SCHEMBL13904227 | 0.75 | L3MBTL1 (0.47) | L3MBTL1KDM4EADORA1KDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073334-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-16 | — | — | US | disclosed |
| WO-2007034278-A2 | FUSED IMIDAZOLE DERIVATIVES AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073334-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | PRKACA, PRKDC, PRKACB | L3MBTL1 2514/4885AR 3387/4885KDM4E 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.