Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922902 | 0.80 | L3MBTL1 (0.48) | L3MBTL1ADORA1CA1CA2CA9 | |
| SCHEMBL19924514 | 0.79 | GLS (0.49) | L3MBTL1ADORA1ALDH1A1MAPTKDM4E | |
| SCHEMBL13904227 | 0.79 | L3MBTL1 (0.47) | L3MBTL1ADORA1CA1CA2CA9 | |
| SCHEMBL15017984 | 0.79 | L3MBTL1 (0.47) | L3MBTL1ADORA1CA1CA2CA9 | |
| SCHEMBL5591663 | 0.79 | L3MBTL1 (0.47) | L3MBTL1ADORA1KMT2APOLBALDH1A1 | |
| SCHEMBL3923269 | 0.77 | L3MBTL1 (0.46) | L3MBTL1ADORA1CA1CA2CA9 | |
| SCHEMBL5598367 | 0.75 | L3MBTL1 (0.43) | L3MBTL1ADORA1KMT2APOLBALDH1A1 | |
| SCHEMBL3211414 | 0.74 | XIAP (0.59) | L3MBTL1ADORA1KMT2APOLBALDH1A1 | |
| SCHEMBL1163357 | 0.74 | PTGS1 (0.54) | L3MBTL1ADORA1ALDH1A1MAPTNPC1 | |
| SCHEMBL15017866 | 0.73 | GLS (0.43) | L3MBTL1ADORA1POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097347-A1 | IMIDAZOPYRIDAZINE DERIVATIVES AS ΡΙ3Κβ INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-06-23 | — | — | WO | disclosed |