Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 15/20 | 0.55 |
| ▸ | CSF1R | P07333 | 12/20 | 0.55 |
| ▸ | KDR | P35968 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598961 | 0.89 | PDGFRB (0.54) | PDGFRBCSF1RKDRKDM4ELMNA | |
| SCHEMBL2176728 | 0.89 | PDGFRB (0.62) | PDGFRBCSF1RKDRFLT3RAB9A | |
| SCHEMBL5598616 | 0.83 | PDGFRB (0.62) | PDGFRBCSF1RKDRFLT3RAB9A | |
| SCHEMBL2173476 | 0.83 | PDGFRB (0.67) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2172313 | 0.81 | PDGFRB (0.57) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598353 | 0.80 | PDGFRB (0.46) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2176128 | 0.76 | MET (0.64) | PDGFRBCSF1RKDRKDM4ELMNA | |
| SCHEMBL5598742 | 0.75 | CSF1R (0.80) | PDGFRBCSF1RKDRLMNAMAPK10 | |
| SCHEMBL2175586 | 0.72 | MET (0.57) | PDGFRBCSF1RKDRKDM4ELMNA | |
| SCHEMBL2173153 | 0.72 | SMN1; SMN2 (0.55) | PDGFRBCSF1RKDRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |