Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14522385 | 0.92 | USP2 (0.44) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL5598558 | 0.85 | PPARA (0.43) | HSD17B10HPGDPTGER4ALDH1A1CYP1A2 | |
| SCHEMBL14521393 | 0.83 | PTGER4 (0.39) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14522391 | 0.80 | STING1 (0.42) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL14522388 | 0.78 | KMT2A (0.35) | HSD17B10HPGDSMN1; SMN2PTGER4ALDH1A1 | |
| SCHEMBL14521330 | 0.78 | STING1 (0.40) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5598246 | 0.77 | LMNA (0.41) | HSD17B10HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1942913 | 0.76 | GLP1R (0.45) | HSD17B10HPGDGAAPTGER4ALDH1A1 | |
| SCHEMBL1943031 | 0.75 | LMNA (0.46) | HSD17B10HPGDGAAPTGER4ALDH1A1 | |
| SCHEMBL5591600 | 0.75 | MAPT (0.39) | HSD17B10HPGDSMN1; SMN2PTGER4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |