SCHEMBL597849

SCHEMBL597849

COc1cc(/C=C/C(=O)c2ccc(O)cc2)ccc1O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.82
CTSL P07711 1/20 0.82
CTSB P07858 1/20 0.82
CXCL12 P48061 10/20 0.82
CXCR4 P61073 1/20 0.80
CHRNA7 P36544 1/20 0.73
TUBB4A P04350 1/20 0.73
TUBB P07437 1/20 0.73
TUBA3C P0DPH7 1/20 0.73
TUBA1B P68363 1/20 0.73
TUBA4A P68366 1/20 0.73
TUBB4B P68371 1/20 0.73
TUBB3 Q13509 1/20 0.73
TUBB2A Q13885 1/20 0.73
TUBB8 Q3ZCM7 1/20 0.73
TUBA3E Q6PEY2 1/20 0.73
TUBA1A Q71U36 1/20 0.73
TUBA1C Q9BQE3 1/20 0.73
TUBB6 Q9BUF5 1/20 0.73
TUBB2B Q9BVA1 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383354 1.00 CAPN1 (0.82) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL597850 1.00 CAPN1 (0.82) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL30383698 1.00 CAPN1 (0.82) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL25198557 0.99 CAPN1 (0.81) CAPN1CTSLCTSBCXCL12CXCR4
Formaldehyde SCHEMBL597329 0.97 CAPN1 (0.79) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL30384490 0.96 CXCL12 (0.89) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL12677857 0.96 CXCL12 (0.89) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL25193952 0.96 CXCL12 (0.89) CAPN1CTSLCTSBCXCL12CXCR4
SCHEMBL5598901 0.91 CXCL12 (0.82) CXCL12CXCR4TUBB4ATUBBTUBA3C
SCHEMBL5598905 0.91 CXCL12 (0.82) CXCL12CXCR4TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170796-B1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT SYMRISE AG (DE) 2012-09-12 EP claimed
US-8115033-B2 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone and use thereof as an antimicrobial active ingredient SYMRISE AG (DE) 2012-02-14 US claimed
US-20100254925-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT SYMRISE GMBH & CO. KG (DE) 2010-10-07 US claimed
EP-2170796-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT Symrise GmbH & Co. KG (DE) 2010-04-07 EP claimed
WO-2009013166-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT SYMRISE GMBH & CO. KG (DE) 2009-01-29 WO claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-11046657-B2 Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-06-29 US disclosed
US-11046657-B2 Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-06-29 US disclosed
US-20200181093-A1 Pyrimidinone Derivatives and Uses Thereof to Neutralize the Biological Activity of Chemokines CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 2020-06-11 US disclosed
EP-2090289-A2 Cosmetic or dermatological preparations with a 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxphenyl)-propan-1-on content and ethylhexyl-2-cyano-3, 3-diphenylacrylate Beiersdorf AG (DE) 2009-08-19 EP disclosed
EP-2090301-A1 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-1-propanon und its use in cosmetic and pharmaceutical preparations Symrise GmbH & Co. KG (DE) 2009-08-19 EP disclosed
EP-2090286-A2 Cosmetic or dermatological preparations with a 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxphenyl)-propan-1-on content and one or more emulgators Beiersdorf AG (DE) 2009-08-19 EP disclosed
EP-2090288-A2 Cosmetic or dermatological preparations with a 3-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxphenyl)-propan-1-on content and one or more cinnamon acid derivatives Beiersdorf AG (DE) 2009-08-19 EP disclosed
WO-2009013168-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND ITS USE AS ANTIOXIDANT SYMRISE GMBH & CO. KG (DE) 2009-01-29 WO disclosed
WO-2009013166-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT SYMRISE GMBH & CO. KG (DE) 2009-01-29 WO disclosed
WO-2009013166-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT SYMRISE GMBH & CO. KG (DE) 2009-01-29 WO disclosed
WO-2007085636-A1 REVERSIBLE THERMOCHROMIC COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181093-A1 Pyrimidinone Derivatives and Uses Thereof to Neutralize the Biological Activity of Chemokines CCL5, CXCR3, CXCL10 CAPN1 4120/4885CTSL 2430/4885CTSB 706/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CAPN1 2288/4885CTSL 357/4885CTSB 51/4885
US-11046657-B2 Pyrimidinone derivatives and uses thereof to neutralize the biological activity of chemokines CCL5, CXCR3, CXCL10 CAPN1 4120/4885CTSL 2430/4885CTSB 706/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CAPN1 1989/4885CTSL 310/4885CTSB 60/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CAPN1 1989/4885CTSL 310/4885CTSB 60/4885
US-20100254925-A1 3-(4-HYDROXY-3-METHOXYPHENYL)-1-(4-HYDROXYPHENYL)-1-PROPANONE AND USE THEREOF AS AN ANTIMICROBIAL ACTIVE INGREDIENT P4HA1, HPD, CYP8B1 CAPN1 1179/4885CTSL 370/4885CTSB 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.