Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | MAOB | P27338 | 9/20 | 0.66 |
| ▸ | P4HB | P07237 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | TFEB | P19484 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598947 | 1.00 | NFKB1 (1.00) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL17068273 | 0.92 | NFKB1 (0.84) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL82266 | 0.87 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL29365331 | 0.87 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL8055837 | 0.87 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL82267 | 0.87 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL5647110 | 0.85 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL6510369 | 0.85 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2MAOA | |
| Hydrochloric Acid SCHEMBL6821798 | 0.85 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2MAOA | |
| SCHEMBL30963014 | 0.85 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC UNM (US) | 2016-02-11 | — | — | US | disclosed |
| US-9187397-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC.UNM | 2015-01-08 | — | — | US | disclosed |
| US-8841326-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2014-09-23 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | NFKB1 418/4885MAOB 1674/4885P4HB 3618/4885 |
| US-20070060644-A1 | Therapeutic curcumin derivatives | FABP2, GLS2, FABP1 | NFKB1 418/4885MAOB 1674/4885P4HB 3618/4885 |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | NFKB1 418/4885MAOB 1674/4885P4HB 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.