Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599385 | 0.88 | CYP1A2 (0.41) | CYP1A2CYP2A6KDM1ANOS3NOS1 | |
| SCHEMBL14866808 | 0.81 | ALDH1A1 (0.38) | POLBMAPTTDP1L3MBTL1AKR1C3 | |
| SCHEMBL21367618 | 0.75 | MAPT (0.49) | POLBMAPTTDP1L3MBTL1KDM1A | |
| SCHEMBL29407167 | 0.74 | CYP2A6 (0.80) | CYP1A2CYP2A6MAPTL3MBTL1AKR1C3 | |
| SCHEMBL347592 | 0.74 | CYP2A6 (0.80) | CYP1A2CYP2A6MAPTL3MBTL1AKR1C3 | |
| SCHEMBL14016921 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP2A6MAPTAKR1C3AKR1C2 | |
| SCHEMBL25847318 | 0.71 | CYP1A2 (0.52) | CYP1A2CYP2A6MAPTAKR1C3AKR1C2 | |
| SCHEMBL12017103 | 0.71 | CYP1A2 (0.61) | CYP1A2CYP2A6L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL14604945 | 0.71 | CYP1A2 (0.61) | CYP1A2CYP2A6MAPTL3MBTL1AKR1C3 | |
| SCHEMBL7729685 | 0.71 | MAOB (0.39) | POLBMAPTTDP1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276633-B2 | Method for production naphthalene derivatives | MERCK PATENT GMBH (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20060025615-A1 | Method for production naphthalene derivatives | MERCK PATENT GMBH (DE) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025615-A1 | Method for production naphthalene derivatives | AOX1, AOC3, CBR3 | CYP1A2 270/4885CYP2A6 646/4885POLB 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.