Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600460 | 0.88 | CHRM3 (0.50) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL27561971 | 0.86 | HTR2C (0.51) | HTR2CHSD17B10SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5599211 | 0.85 | HSD17B10 (0.51) | HSD17B10RIPK1 | |
| Hydrochloric Acid SCHEMBL7669676 | 0.84 | HTR2C (0.53) | HTR2CHSD17B10SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5133970 | 0.83 | HSD17B10 (0.50) | HSD17B10RIPK1 | |
| SCHEMBL7676995 | 0.83 | HTR2C (0.53) | HTR2CHSD17B10SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL11161743 | 0.82 | HSD17B10 (0.49) | HSD17B10RIPK1 | |
| SCHEMBL5660577 | 0.82 | MDM4 (0.50) | HTR2CHSD17B10SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7672523 | 0.82 | ALDH1A1 (0.53) | HTR2CHSD17B10SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7666631 | 0.82 | HTR2C (0.54) | HTR2CHSD17B10SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497303-B1 | Carbamic acid derivatives and method for preparing the same | KYORIN SEIYAKU KK (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5300515-A | Cognition activators for brain disorders; alzheimer*s disease | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0497303-A2 | Carbamic acid derivatives and method for preparing the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |