Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 8/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.41 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110402 | 0.86 | P2RY12 (0.49) | P2RY12 | |
| SCHEMBL4110320 | 0.81 | MEN1 (0.49) | P2RY12 | |
| SCHEMBL2417886 | 0.81 | CXCR3 (0.54) | CXCR3P2RY12 | |
| SCHEMBL3927688 | 0.78 | KMT2A (0.58) | — | |
| SCHEMBL24970972 | 0.77 | CXCR3 (0.63) | CXCR3P2RY12 | |
| SCHEMBL31142964 | 0.77 | CXCR3 (0.63) | CXCR3P2RY12 | |
| SCHEMBL4500021 | 0.77 | CXCR3 (0.43) | CXCR3P2RY12SLC2A1 | |
| Hydrochloric Acid SCHEMBL30903328 | 0.77 | CXCR3 (0.62) | CXCR3P2RY12 | |
| SCHEMBL2418989 | 0.76 | SMN1; SMN2 (0.50) | CXCR3P2RY12 | |
| SCHEMBL5592425 | 0.76 | P2RY12 (0.54) | P2RY12USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |