Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5600190 | 0.91 | GNRHR (0.36) | GNRHRKCNH2 | |
| SCHEMBL5785804 | 0.88 | KMT2A (0.36) | GNRHR | |
| SCHEMBL5780422 | 0.85 | P2RX7 (0.36) | GNRHRKCNH2DPP4 | |
| SCHEMBL5786887 | 0.85 | GNRHR (0.41) | GNRHRKCNH2 | |
| SCHEMBL5786885 | 0.85 | GNRHR (0.33) | GNRHRKCNH2DPP4 | |
| SCHEMBL5780824 | 0.81 | GNRHR (0.37) | GNRHRKCNH2DPP4 | |
| SCHEMBL5599124 | 0.81 | GNRHR (0.34) | GNRHRKCNH2DPP4 | |
| SCHEMBL5599977 | 0.81 | GNRHR (0.34) | GNRHRKCNH2DPP4 | |
| SCHEMBL5788610 | 0.81 | GNRHR (0.34) | GNRHRKCNH2DPP4 | |
| SCHEMBL5784847 | 0.80 | GNRHR (0.34) | GNRHRKCNH2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063745-A9 | NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF | ARENA PHARM INC (US) | 2007-02-01 | — | — | WO | claimed |