Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5600116 | 0.86 | KDM4E (0.31) | KDM4EATM | |
| Hydrochloric Acid SCHEMBL5602208 | 0.81 | CA1 (0.39) | KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5601658 | 0.81 | CA1 (0.40) | KDM4EL3MBTL1 | |
| Fluoride Ion SCHEMBL5601165 | 0.79 | CA1 (0.40) | KDM4EL3MBTL1 | |
| Bromide SCHEMBL5602390 | 0.79 | CA1 (0.40) | KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5603754 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL5600394 | 0.77 | KDM4E (0.36) | KDM4EATML3MBTL1GPR3POLB | |
| SCHEMBL6064889 | 0.77 | KDM4E (0.36) | KDM4EATML3MBTL1GPR3POLB | |
| Hydrochloric Acid SCHEMBL5602762 | 0.77 | KDM4E (0.36) | KDM4EATML3MBTL1GPR3POLB | |
| Hydrochloric Acid SCHEMBL5602530 | 0.77 | MAPT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |