SCHEMBL6064889

SCHEMBL6064889

F[Zr](F)C1C(n2c3ccccc3c3ccccc32)=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GPR3 P46089 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603527 0.82 KDM4E (0.33) KDM4EATML3MBTL1
Hydrochloric Acid SCHEMBL5599787 0.77 KDM4E (0.36) KDM4EATML3MBTL1GPR3POLB
SCHEMBL5602139 0.76 KDM4E (0.35) KDM4EATML3MBTL1
Fluoride Ion SCHEMBL6064887 0.75 KDM4E (0.37) KDM4EATML3MBTL1GPR3POLB
Hydrochloric Acid SCHEMBL5600394 0.74 KDM4E (0.36) KDM4EATML3MBTL1GPR3POLB
Fluoride Ion SCHEMBL5602127 0.74 KDM4E (0.36) KDM4EATML3MBTL1GPR3POLB
Hydrochloric Acid SCHEMBL5602762 0.74 KDM4E (0.36) KDM4EATML3MBTL1GPR3POLB
Bromide SCHEMBL5602659 0.74 KDM4E (0.36) KDM4EATML3MBTL1GPR3POLB
SCHEMBL5599790 0.74 KDM4E (0.36) KDM4EATML3MBTL1GPR3POLB
SCHEMBL5602777 0.73 KDM4E (0.35) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed