Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 5/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239213 | 0.86 | PIK3CA (0.34) | PIK3CAXDHDRD4 | |
| SCHEMBL15822831 | 0.81 | EZH2 (0.32) | PIK3CABRD4BAZ2A | |
| SCHEMBL1833324 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL12239226 | 0.79 | BRD4 (0.36) | BRD4BAZ2A | |
| SCHEMBL12239253 | 0.78 | PIK3CA (0.31) | PIK3CADRD4 | |
| SCHEMBL560005 | 0.78 | DAO (0.30) | — | |
| SCHEMBL15839576 | 0.78 | — | — | |
| SCHEMBL12239237 | 0.78 | PIK3CA (0.34) | PIK3CAXDHDRD4 | |
| SCHEMBL1652645 | 0.77 | NPC1 (0.31) | BRD4BAZ2A | |
| SCHEMBL15822060 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735322-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-05-27 | — | — | US | disclosed |
| EP-2350034-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20120035053-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| EP-2350034-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010046194-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035053-A1 | NOVEL HERBICIDES | DDT, HCAR3, HPD | PIK3CA 2894/4885XDH 1693/4885DRD4 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.