Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Vinyl Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | BLM | P54132 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28811019 | 0.81 | — | — | |
| Succinic Acid SCHEMBL28071063 | 0.80 | LMNA (0.53) | OR51E2GABRR1TSHRBLMCYP2D6 | |
| Glycine SCHEMBL1148008 | 0.79 | — | — | |
| Vinyl Ether SCHEMBL9622539 | 0.79 | — | — | |
| Glycine SCHEMBL21986685 | 0.79 | GLRA1 (0.50) | GLRA1SLC6A9OR51E2GABRR1TSHR | |
| Vinyl Ether SCHEMBL1226757 | 0.78 | — | — | |
| Vinyl Ether SCHEMBL29064322 | 0.78 | FFAR3 (0.56) | TSHRCYP2D6LMNAHDAC3HDAC1 | |
| Glycine SCHEMBL21986687 | 0.77 | GLRA1 (0.48) | GLRA1SLC6A9OR51E2GABRR1TSHR | |
| Acetoacetic Acid SCHEMBL9184451 | 0.77 | KDM4E (0.39) | TSHRLMNAALDH1A1ALOX15HSD17B10 | |
| Glycine SCHEMBL4169207 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570916-B1 | Long-term general-purpose water repellant | ECO COSMO CO LTD (JP) | 2007-12-05 | — | — | EP | disclosed |
| US-20050197439-A1 | Long-term general-purpose water repellant | MIN-EKI CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| EP-1570916-A1 | Long-term general-purpose water repellant | MIN-EKI CO., LTD. (JP) | 2005-09-07 | — | — | EP | disclosed |