Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.68 |
| ▸ | TNKS | O95271 | 1/20 | 0.68 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.68 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818746 | 1.00 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL560054 | 1.00 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL27548448 | 1.00 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL436113 | 0.98 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL474728 | 0.98 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL15119 | 0.98 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL144681 | 0.98 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL144680 | 0.98 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL11522747 | 0.98 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Juarezic Acid SCHEMBL3280210 | 0.96 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288168-A1 | HISTONE DEACETYLASE INHIBITORS | ERRANT GENE THERAPEUTICS, LLC | 2011-11-24 | — | — | US | claimed |
| US-7842727-B2 | Histone deacetylase inhibitors | ERRANT GENE THERAPEUTICS, LLC (US) | 2010-11-30 | — | — | US | claimed |
| WO-2008011074-A2 | HISTONE DEACETYLASE INHIBITORS | ERRANT GENE THERAPEUTICS, LLC (US) | 2008-01-24 | — | — | WO | claimed |
| US-20070037869-A1 | Treating spinal muscular atrophy with an effective amount of carboxylic acid derivative or hydroxamic acid derivative compound; treating cancer, blood disorders, genetic related metabolic disorders; 5-phenyl-2,4-pentadienoic acid | ERRANT GENE THERAPEUTICS, LLC | 2007-02-15 | — | — | US | claimed |
| EP-1408946-A4 | HISTONE DEACETYLASE INHIBITORS | CIRCAGEN PHARMACEUTICAL (US) | 2004-06-09 | — | — | EP | claimed |
| EP-1408946-A2 | HISTONE DEACETYLASE INHIBITORS | Circagen Pharmaceutical (US) | 2004-04-21 | — | — | EP | claimed |
| EP-1260626-A2 | Process for bonding fibrous web | CAMELOT SUPERABSORBENTS LTD (CA) | 2002-11-27 | — | — | EP | claimed |
| WO-2002076941-A2 | HISTONE DEACETYLASE INHIBITORS | CIRCAGEN PHARMACEUTICAL (US) | 2002-10-03 | — | — | WO | claimed |
| US-20020143052-A1 | Histone deacetylase inhibitors | ANGELA CHEN SABELLA | 2002-10-03 | — | — | US | claimed |
| US-20020143037-A1 | Histone deacetylase inhibitors | CIRCAGEN PHARMACEUTICAL, A DELAWARE CORPORATION | 2002-10-03 | — | — | US | claimed |
| EP-0956385-A1 | PROCESS FOR BONDING FIBROUS WEB | CAMELOT SUPERABSORBENTS LTD (CA) | 1999-11-17 | — | — | EP | claimed |
| WO-1998032906-A1 | PROCESS FOR BONDING FIBROUS WEB | CAMELOT SUPERABSORBENTS LIMITED (CA) | 1998-07-30 | — | — | WO | claimed |
| US-3950600-A | Thermosensitive element, and its employ in the thermographic reproduction or record systems | ING. C. OLIVETTI & C., S.P.A. (IT) | 1976-04-13 | — | — | US | claimed |
| US-9486421-B2 | Treatment of lung cells with histone deacetylase inhibitors | ERRANT GENE THERAPEUTICS, LLC (US) | 2016-11-08 | — | — | US | disclosed |
| EP-2489521-B1 | HEAT-SENSITIVE RECORDING MATERIAL | OJI HOLDINGS CORP (JP) | 2013-12-11 | — | — | EP | disclosed |
| US-8420698-B2 | Histone deacetylase inhibitors | ERRANT GENE THERAPEUTICS, LLC (US) | 2013-04-16 | — | — | US | disclosed |
| EP-0101319-B1 | FIBROUS WEBS OF ENHANCED BULK AND METHOD OF MANUFACTURING SAME | James River-Norwalk, Inc. (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4488932-A | HAMMER MILLING, DISPERSION IN AQUEOUS FOAM, PAPERMAKING | JAMES RIVER-DIXIE/NORTHERN, INC. (US) | 1984-12-18 | — | — | US | disclosed |
| EP-0101319-A2 | Fibrous webs of enhanced bulk and method of manufacturing same | James River-Norwalk, Inc. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-3950600-A | Thermosensitive element, and its employ in the thermographic reproduction or record systems | ING. C. OLIVETTI & C., S.P.A. (IT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143052-A1 | Histone deacetylase inhibitors | HDAC1, HDAC11, HDAC9 | HDAC3 7/4885HDAC4 14/4885HDAC1 1/4885 |
| US-20020143037-A1 | Histone deacetylase inhibitors | HDAC1, HDAC9, HDAC11 | HDAC3 5/4885HDAC4 13/4885HDAC1 1/4885 |
| US-20110288168-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC6, HDAC5 | HDAC3 6/4885HDAC4 10/4885HDAC1 1/4885 |
| US-20070037869-A1 | Treating spinal muscular atrophy with an effective amount of carboxylic acid derivative or hydroxamic acid derivative compound; treating cancer, blood disorders, genetic related metabolic disorders; 5-phenyl-2,4-pentadienoic acid | HDAC5, HDAC1, ZNF277 | HDAC3 7/4885HDAC4 16/4885HDAC1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.