Juarezic Acid

Juarezic Acid

SCHEMBL3280210

N.O=C(O)C=CC=Cc1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.68
HDAC4 P56524 3/20 0.68
HDAC1 Q13547 3/20 0.68
HDAC2 Q92769 3/20 0.68
HDAC8 Q9BY41 3/20 0.68
HDAC6 Q9UBN7 3/20 0.68
HDAC7 Q8WUI4 2/20 0.68
HDAC10 Q969S8 2/20 0.68
HDAC11 Q96DB2 2/20 0.68
HDAC9 Q9UKV0 2/20 0.68
HDAC5 Q9UQL6 2/20 0.68
TNKS O95271 1/20 0.68
HCAR2 Q8TDS4 1/20 0.68
TNKS2 Q9H2K2 1/20 0.68
MAOB P27338 8/20 0.61
ALDH1A1 P00352 3/20 0.56
MAPT P10636 3/20 0.56
CYP1A2 P05177 3/20 0.56
LMNA P02545 3/20 0.56
CYP2D6 P10635 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Juarezic Acid SCHEMBL436113 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL144681 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL144680 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL11522747 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL474728 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL15119 0.98 HDAC3 (0.71) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL2335383 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL30239689 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL560728 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL5399197 0.96 HDAC3 (0.68) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728529-B Thermosensitive recording medium 大阪希琳阁印刷株式会社 2024-09-27 CN claimed
CN-114728529-A Thermosensitive recording medium 大阪希琳阁印刷株式会社 2022-07-08 CN claimed
US-20200268634-A1 EYE MAKE-UP COSMETIC COMPOSITION COMPRISING ACRYLATE-BASED COPOLYMER COSMAX, INC. (KR) 2020-08-27 US claimed
US-20030180229-A1 Bleach stable toothpaste KOSTI CARL M (US) 2003-09-25 US claimed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US claimed
CN-115777700-B Suspending agent containing metribuzin and haloxyfop-methyl and preparation method thereof 山东润博生物科技有限公司 2024-11-08 CN disclosed
CN-114728529-B Thermosensitive recording medium 大阪希琳阁印刷株式会社 2024-09-27 CN disclosed
EP-4149409-A1 NOVEL ENCAPSULATED COSMETIC COMPOSITIONS AND USES THEREOF ELC Management LLC (US) 2023-03-22 EP disclosed
US-20230000742-A1 HAIR-STRAIGHTENING COMPOSITIONS BEAUTY & BUSINESS S.P.A. (IT) 2023-01-05 US disclosed
CN-114728529-A Thermosensitive recording medium 大阪希琳阁印刷株式会社 2022-07-08 CN disclosed
WO-2021231665-A1 NOVEL ENCAPSULATED COSMETIC COMPOSITIONS AND USES THEREOF ELC MANAGEMENT LLC (US) 2021-11-18 WO disclosed
US-20210353512-A1 NOVEL ENCAPSULATED COSMETIC COMPOSITIONS AND USES THEREOF ELC MAN LLC (US) 2021-11-18 US disclosed
US-5760121-A FOR MATRIX POLYMER PLATELET COMPOSITES; HEAT RESISTANCE AMCOL INTERNATIONAL CORPORATION (US) 1998-06-02 US disclosed
US-5730996-A Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1998-03-24 US disclosed
US-5721306-A EXFOLIATED PLATELETS FORMED BY CONTACTING LAYERED SILICATE MATERIAL WITH INTERCALANT POLYMER AMCOL INTERNATIONAL CORPORATION (US) 1998-02-24 US disclosed
EP-0808568-A1 Intercalates and exfoliates formed with organic pesticide compounds and compositions containing the same AMCOL INTERNATIONAL CORPORATION (US) 1997-11-26 EP disclosed
EP-0747323-A1 Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1996-12-11 EP disclosed
EP-0747451-A2 Intercalates and exfoliates formed with oligomers and polymers and composite materials containing same AMCOL INTERNATIONAL CORPORATION (US) 1996-12-11 EP disclosed
US-5578672-A MIXING PHYLLOSILICATE WITH A POLYMER AND LIQUID CARRIER, EXTRUSION THROUGH DIE; COMPOSITES, AUTOMOBILE PARTS AMCOL INTERNATIONAL CORPORATION (US) 1996-11-26 US disclosed
US-5552469-A SILICATE AMCOL INTERNATIONAL CORPORATION (US) 1996-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210353512-A1 NOVEL ENCAPSULATED COSMETIC COMPOSITIONS AND USES THEREOF CUTA, TYR, NACA HDAC3 140/4885HDAC4 80/4885HDAC1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.