SCHEMBL5600593

SCHEMBL5600593

Cc1ccc2c(c1Cc1ccccc1)[N]c1ccccc1O2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.36
NQO1 P15559 2/20 0.35
CNR2 P34972 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
HPGD P15428 4/20 0.33
MAPK1 P28482 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
GAA P10253 2/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 5/20 0.32
ALDH1A1 P00352 5/20 0.32
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
ELANE P08246 1/20 0.32
GLA P06280 1/20 0.32
HSD17B3 P37058 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603142 0.83 MAPK1 (0.35) MAPK1MAPT
SCHEMBL5601526 0.81 NOS2 (0.35) HPGDMAPK1RAB9AGAAKDM4E
SCHEMBL5601456 0.79 CYP1A1 (0.35) HPGDMAPK1NPC1RAB9ATSHR
SCHEMBL5602904 0.78 CYP1A1 (0.36) HPGDGAAKDM4EALDH1A1HSD17B10
SCHEMBL5599911 0.77 CYP1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10
SCHEMBL5601549 0.77 CYP1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10
SCHEMBL5600729 0.77 CYP1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10
SCHEMBL5601413 0.77 CYP1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10
SCHEMBL5603212 0.77 CYP1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10
SCHEMBL5603940 0.77 CYP1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed