SCHEMBL5603142

SCHEMBL5603142

CCc1c(C)ccc2c1[N]c1ccccc1O2

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
TRPA1 O75762 3/20 0.33
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
AHR P35869 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601526 0.88 NOS2 (0.35) MAPK1TRPA1NOS2CYP1A2
SCHEMBL5601456 0.86 CYP1A1 (0.35) MAPK1TRPA1NOS2CYP1A2MEN1
SCHEMBL5602904 0.85 CYP1A1 (0.36) MEN1KMT2A
SCHEMBL5602034 0.84 MAOA (0.36) MAPK1TRPA1CYP1A2CYP2D6AHR
SCHEMBL5603940 0.84 CYP1A1 (0.38)
SCHEMBL5603212 0.84 CYP1A1 (0.38)
SCHEMBL5601549 0.84 CYP1A1 (0.38)
SCHEMBL5599911 0.84 CYP1A1 (0.38)
SCHEMBL5600729 0.84 CYP1A1 (0.38)
SCHEMBL5601413 0.84 CYP1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed