Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094629 | 0.85 | C3AR1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3082719 | 0.85 | MAPT (0.42) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3078136 | 0.81 | RAB9A (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9569910 | 0.77 | PTPN1 (0.40) | CALM1PTPN1MAOBMAPK1CYP1A2 | |
| SCHEMBL5603177 | 0.75 | SMN1; SMN2 (0.35) | ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5601388 | 0.73 | SMN1; SMN2 (0.38) | CALM1LTB4RAOC3NPC1RAB9A | |
| SCHEMBL1815962 | 0.72 | KDM4E (0.33) | ALDH1A1HPGDELANE | |
| SCHEMBL5602078 | 0.69 | KDM4E (0.33) | ALDH1A1PTPN1ELANENR1H2NR1H3 | |
| SCHEMBL5601077 | 0.68 | KCNH2 (0.39) | PTPN1NR1H2NR1H3TDP1L3MBTL1 | |
| SCHEMBL482253 | 0.67 | CYP1A2 (0.42) | ALDH1A1SMN1; SMN2CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |
| CN-1125044-C | Novel prostaglandin synthase inhibitors | DU PONT MERCK PHARMA (US) | 2003-10-22 | — | — | CN | disclosed |