Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18887420 | 0.74 | ALDH1A1 (0.45) | CYP1A2CYP2C9MAPK1TDP1 | |
| SCHEMBL6115343 | 0.70 | GPR84 (0.58) | — | |
| SCHEMBL2339223 | 0.69 | CALM1 (0.42) | PTPN1CALM1MAOBCYP2C9ELANE | |
| SCHEMBL10733624 | 0.67 | CALM1 (0.50) | PTPN1CALM1MAOBCYP1A2CYP2C9 | |
| SCHEMBL2072302 | 0.66 | CDC25B (0.39) | MAOBCYP1A2CYP2C9MAPK1HIF1A | |
| SCHEMBL3698764 | 0.66 | MEN1 (0.36) | MAOBMAPK1MAOATDP1 | |
| SCHEMBL3082719 | 0.64 | MAPT (0.42) | CYP1A2MAPK1TDP1L3MBTL1 | |
| SCHEMBL6491993 | 0.64 | CALM1 (0.41) | CALM1MAOBCYP1A2CYP2C9MAPK1 | |
| SCHEMBL17727973 | 0.63 | TDP1 (0.52) | PTPN1CALM1MAOBCYP1A2CYP2C9 | |
| SCHEMBL13265639 | 0.62 | CALM1 (0.38) | PTPN1CALM1MAOBCYP1A2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564805-A1 | (4-benzylphthalazin-1(2H)-on-2-yl)aminocarboxylic acids having antiallergic/antihistaminic activity and process for their production | ASTA Medica Aktiengesellschaft (DE) | 1993-10-13 | — | — | EP | disclosed |