Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30810156 | 0.95 | DHODH (0.63) | PKMKMT2AMEN1MAPTGRIK1 | |
| SCHEMBL6154631 | 0.91 | DHODH (0.77) | PKMKMT2AMEN1MAPTGRIK1 | |
| SCHEMBL5117801 | 0.87 | POLB (0.57) | PKMKMT2AMEN1DHODHKDM4E | |
| SCHEMBL3711733 | 0.87 | DHODH (0.57) | PKMKMT2AMEN1MAPTTDP1 | |
| SCHEMBL3381862 | 0.87 | POLB (0.56) | PKMKMT2AMEN1MAPTGRIK1 | |
| SCHEMBL28552726 | 0.87 | PDCD1 (0.63) | PKMKMT2AMEN1MAPTGRIK1 | |
| SCHEMBL414754 | 0.85 | MEN1 (0.83) | PKMKMT2AMEN1MAPTGRIK1 | |
| SCHEMBL31053873 | 0.85 | MEN1 (0.83) | PKMKMT2AMEN1MAPTGRIK1 | |
| SCHEMBL9129050 | 0.84 | TSHR (0.61) | PKMKMT2AMEN1MAPTKDM4E | |
| SCHEMBL8439303 | 0.84 | MEN1 (0.80) | PKMKMT2AMEN1MAPTGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294345-B2 | Otorhinological delivery device | SCHERING OY (FI) | 2007-11-13 | — | — | US | disclosed |
| US-20060067982-A1 | Otorhinological delivery device | TIMO HAAPAKUMPU HARRI JUKARA JUHA ALA -SORVARI HEN (FI) | 2006-03-30 | — | — | US | disclosed |
| WO-2004064912-A1 | AN OTORHINOLOGICAL DELIVERY DEVICE | SCHERING OY (FI) | 2004-08-05 | — | — | WO | disclosed |
| EP-0726761-B1 | MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM | ISOMED INC (US) | 2001-01-10 | — | — | EP | disclosed |
| US-5858398-A | MICROPARTICLES CONTAINING ACTIVE AGENT, MIXTURE OF PHOSPHOLIPIDS, MIXTURE OF NONIONIC SURFACTANTS, STEROL SUSPENDED IN FATTY ACID | ISOMED INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0726761-A1 | MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM | ISOTECH MEDICAL, INC. (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012385-A1 | MICROPARTICULAR PHARMACEUTICAL COMPOSITIONS IN MICELLAR FORM | ISOTECH MEDICAL, INC. (US) | 1995-05-11 | — | — | WO | disclosed |