SCHEMBL5601339

SCHEMBL5601339

FC(F)(F)C1=c2ccccc2=C[N]1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603810 0.65 CYP1A2 (0.32) TSHR
SCHEMBL6293154 0.65 MAPT (0.30)
SCHEMBL5057510 0.61
SCHEMBL5601756 0.61 HSD11B1 (0.32) ALDH1A1TSHR
SCHEMBL5129685 0.61 TSHR (0.32) TSHR
SCHEMBL5051714 0.61
SCHEMBL5602183 0.61 TP53 (0.32)
SCHEMBL5601073 0.58 KDM4E (0.33) ALDH1A1
SCHEMBL5601885 0.57
SCHEMBL5602658 0.57 CYP11B2 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed