Phosphinothricin

Phosphinothricin

SCHEMBL5601699

CP(=O)(O)CC[C@H](N)C(=O)O.C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CCP(C)(=O)O)C(=O)O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GLUL P15104 1/20 0.43
GCLC P48506 1/20 0.42
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRM7 Q14831 1/20 0.42
GRM4 Q14833 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glufosinate SCHEMBL7468438 1.00 GLUL (0.43) GLULGCLCGRM8GRM6GRM7
SCHEMBL54688 0.97 GLUL (0.38) GLULGCLCGRM8GRM6GRM7
SCHEMBL910217 0.97 GLUL (0.38) GLULGCLCGRM8GRM6GRM7
SCHEMBL29592595 0.97 GLUL (0.38) GLULGCLCGRM8GRM6GRM7
SCHEMBL3634376 0.97 GLUL (0.38) GLULGCLCGRM8GRM6GRM7
SCHEMBL18706 0.97 GLUL (0.38) GLULGCLCGRM8GRM6GRM7
SCHEMBL1202986 0.96 LTA4H (0.37) GLULGCLCGRM8GRM6GRM7
SCHEMBL10745013 0.96 LTA4H (0.37) GLULGCLCGRM8GRM6GRM7
SCHEMBL2790167 0.96 LTA4H (0.37) GLULGCLCGRM8GRM6GRM7
SCHEMBL9859876 0.94 GLUL (0.40) GLULGCLCGRM8GRM6GRM7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1825753-A2 Solid herbicidal composition ISHIHARA SANGYO KAISHA, LTD. (JP) 2007-08-29 EP claimed
US-10876131-B2 Dig-303 insecticidal Cry toxins DOW AGROSCIENCES LLC (US) 2020-12-29 US disclosed
US-10731176-B2 DIG-305 insecticidal Cry toxins DOW AGROSCIENCES LLC (US) 2020-08-04 US disclosed
US-20200184403-A1 ENGINEERED CRY6A INSECTICIDAL PROTEINS DOW AGROSCIENCES LLC (US) 2020-06-11 US disclosed
US-10612036-B2 Engineered Cry6A insecticidal proteins DOW AGROSCIENCES LLC (US) 2020-04-07 US disclosed
US-10028510-B2 DIG-17 insecticidal cry toxins DOW AGROSCIENCES LLC (US) 2018-07-24 US disclosed
EP-3337903-A1 ENGINEERED CRY6A INSECTICIDAL PROTEINS Dow Agrosciences LLC (US) 2018-06-27 EP disclosed
US-20170369538-A1 DIG-305 INSECTICIDAL CRY TOXINS DOW AGROSCIENCES LLC (US) 2017-12-28 US disclosed
EP-3240900-A1 DIG-305 INSECTICIDAL CRY TOXINS Dow Agrosciences LLC (US) 2017-11-08 EP disclosed
EP-3212004-A1 DIG-303 INSECTICIDAL CRY TOXINS Dow Agrosciences LLC (US) 2017-09-06 EP disclosed
US-20160060306-A1 DIG-14 INSECTICIDAL CRY TOXINS CORTEVA AGRISCIENCE LLC 2016-03-03 US disclosed
EP-1102528-A4 TRANSLATION CONTROL ELEMENTS FOR HIGH-LEVEL PROTEIN EXPRESSION IN THE PLASTIDS OF HIGHER PLANTS AND METHODS OF USE THEREOF UNIV RUTGERS (US) 2005-03-02 EP disclosed
US-20030014775-A1 Compositions and method for modulation of gene expression in plants RIBOZYME PHARMACEUTICALS, INC. 2003-01-16 US disclosed
US-6350934-B1 A NUCLEIC ACID; PRODUCING TRANSGENIC PLANTS WITH DECREASED UNSATURATED FATTY ACID PRODUCTION RIBOZYME PHARMACEUTICALS, INC. 2002-02-26 US disclosed
EP-1102528-A1 TRANSLATION CONTROL ELEMENTS FOR HIGH-LEVEL PROTEIN EXPRESSION IN THE PLASTIDS OF HIGHER PLANTS AND METHODS OF USE THEREOF RUTGERS UNIVERSITY (US) 2001-05-30 EP disclosed
WO-2000007431-A1 TRANSLATION CONTROL ELEMENTS FOR HIGH-LEVEL PROTEIN EXPRESSION IN THE PLASTIDS OF HIGHER PLANTS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2000-02-17 WO disclosed
CN-1196091-A Compositions and method for modulation of gene expression in plants RIBOZYME PHARM INC (US) 1998-10-14 CN disclosed
WO-1998032843-A2 COMPOSITIONS AND METHOD FOR MODULATION OF ALKALOID BIOSYNTHESIS AND FLOWER FORMATION IN PLANTS RIBOZYME PHARMACEUTICALS, INC. (US) 1998-07-30 WO disclosed
EP-0842286-A2 COMPOSITIONS AND METHOD FOR MODULATION OF GENE EXPRESSION IN PLANTS RIBOZYME PHARMACEUTICALS, INC. (US) 1998-05-20 EP disclosed
WO-1997010328-A2 COMPOSITIONS AND METHOD FOR MODULATION OF GENE EXPRESSION IN PLANTS RIBOZYME PHARMACEUTICALS, INC. (US) 1997-03-20 WO disclosed