Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603887 | 0.93 | KCNH2 (0.42) | KCNH2LIPGSIGMAR1CYP3A4CHRM2 | |
| SCHEMBL5603147 | 0.91 | KCNH2 (0.44) | KCNH2LIPGCYP3A4CHRM2ADRA2A | |
| SCHEMBL5603914 | 0.86 | KDM4E (0.34) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5602070 | 0.69 | LIPG (0.36) | KCNH2LIPGSIGMAR1 | |
| Butylbenzyl SCHEMBL27588763 | 0.69 | SIGMAR1 (0.57) | KCNH2SIGMAR1HSD11B1CA1CA2 | |
| SCHEMBL5599626 | 0.68 | TDP1 (0.38) | KCNH2LIPGSIGMAR1TLR8HSD11B1 | |
| SCHEMBL5601800 | 0.67 | LIPG (0.39) | KCNH2LIPGCYP3A4CHRM2ADRA2A | |
| SCHEMBL29520482 | 0.67 | LIPG (0.56) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL245188 | 0.67 | LIPG (0.56) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2049761 | 0.65 | LIPG (0.54) | LIPGTLR8CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |