Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5601643 | 0.92 | MEN1 (0.39) | KMT2AMEN1ALOX15TSHRCYP19A1 | |
| Hydrochloric Acid SCHEMBL5603301 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL5602973 | 0.82 | ADH5 (0.36) | KMT2AMEN1ALOX15TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL6064859 | 0.81 | KMT2A (0.34) | KMT2AMEN1ALOX15TSHRCYP19A1 | |
| Hydrochloric Acid SCHEMBL5601276 | 0.81 | MEN1 (0.31) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5600863 | 0.80 | KMT2A (0.36) | KMT2A | |
| Hydrochloric Acid SCHEMBL5601947 | 0.80 | CYP3A4 (0.39) | KMT2AMEN1CYP19A1 | |
| Hydrochloric Acid SCHEMBL5600578 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5604034 | 0.79 | — | — | |
| SCHEMBL6064860 | 0.78 | IDO1 (0.34) | KMT2AMEN1ALOX15TSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |