SCHEMBL5602471

SCHEMBL5602471

CCCc1cccc2c1[N]c1ccccc1O2

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
TRPA1 O75762 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
ELANE P08246 2/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
GRM5 P41594 1/20 0.31
ALOX5 P09917 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601859 0.90 LIPG (0.36) MAOATRPA1CYP2D6ALOX5
SCHEMBL5601327 0.89 LIPG (0.41) ALOX5
SCHEMBL5600669 0.88 LIPG (0.44) ALOX5
SCHEMBL5603162 0.88 LIPG (0.44) ALOX5
SCHEMBL5602924 0.88 LIPG (0.44) ALOX5
SCHEMBL5601382 0.88 LIPG (0.44) ALOX5
SCHEMBL5603403 0.88 LIPG (0.44) ALOX5
SCHEMBL5603739 0.88 LIPG (0.44) ALOX5
SCHEMBL5601963 0.88 LIPG (0.44) ALOX5
SCHEMBL5601488 0.86 MAOA (0.45) MAOATRPA1CYP1A2CYP2D6HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed