Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602494 | 0.76 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2IDO1TSHR | |
| SCHEMBL3629164 | 0.74 | IDO1 (0.48) | NPC1RAB9AIDO1GAAALDH1A1 | |
| SCHEMBL324748 | 0.73 | SMN1; SMN2 (0.32) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL1404502 | 0.69 | MAPT (0.36) | NPC1RAB9ASMN1; SMN2IDO1TSHR | |
| SCHEMBL5601381 | 0.68 | TAAR1 (0.36) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL28425344 | 0.68 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL197690 | 0.68 | ACHE (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL30354037 | 0.68 | ACHE (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL30169568 | 0.68 | ACHE (0.64) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL1775278 | 0.67 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |