Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.60 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.60 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.60 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525519 | 0.81 | ALDH1A1 (0.72) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8218590 | 0.78 | NPC1 (0.71) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6159150 | 0.76 | SMN1; SMN2 (0.66) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL4650800 | 0.75 | HIF1A (0.57) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8222658 | 0.75 | KMT2A (0.64) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8162947 | 0.74 | HIF1A (0.72) | ALDH1A1HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23417641 | 0.74 | SMN1; SMN2 (0.84) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL14241870 | 0.74 | ALDH1A1 (0.71) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL17790726 | 0.74 | CNR1 (0.68) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL14991782 | 0.74 | SMN1; SMN2 (0.62) | ALDH1A1TAAR1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007070816-A2 | THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |