SCHEMBL5603283

SCHEMBL5603283

Cc1ccccc1C1CCCC2=C1[N]c1ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
HTR2C P28335 4/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADRA2A P08913 3/20 0.32
ADRA1A P35348 3/20 0.32
ADRA1D P25100 2/20 0.32
ADRA1B P35368 2/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
HTR2A P28223 2/20 0.31
HTR2B P41595 2/20 0.31
HRH3 Q9Y5N1 2/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601420 0.87 BCHE (0.33)
SCHEMBL5604200 0.81 CYP19A1 (0.36) ALDH1A1TNKS2
SCHEMBL5602761 0.80 IGF1R (0.38) DDB1CRBNL3MBTL1CYP11B2
SCHEMBL5603963 0.76 HRH3 (0.35) HRH3
SCHEMBL5603094 0.75 CYP26A1 (0.37)
SCHEMBL5601110 0.72 ACHE (0.30)
SCHEMBL5603153 0.72 NR1I2 (0.30) PBRM1
SCHEMBL5602313 0.72 DDB1 (0.43) DDB1CRBNHTR2CKDM4EALDH1A1
SCHEMBL5603618 0.72 NOS1 (0.32)
SCHEMBL5600266 0.71 ACE (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed