SCHEMBL5603291

SCHEMBL5603291

Cc1cccc2c1N=C(C(F)(F)F)[N]2

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.31
APAF1 O14727 1/20 0.30
USP2 O75604 1/20 0.30
PLCG1 P19174 1/20 0.30
CCR6 P51684 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603711 0.74 CYP2A6 (0.40)
SCHEMBL2071909 0.71 ALDH1A1 (0.35) APAF1USP2PLCG1CCR6TDP1
SCHEMBL907983 0.71 ALDH1A1 (0.35) APAF1USP2PLCG1CCR6TDP1
SCHEMBL5600877 0.68 CYP1A2 (0.30)
SCHEMBL5603289 0.67 HSD11B1 (0.36) L3MBTL1
SCHEMBL5601779 0.67 ALDH1A1 (0.36) L3MBTL1
SCHEMBL5603766 0.66 TSHR (0.30)
SCHEMBL5599958 0.66 NPC1 (0.35) TDP1
SCHEMBL3819593 0.64 CYP2A6 (0.41)
SCHEMBL5601012 0.63 KCNH2 (0.33) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed