SCHEMBL5603359

SCHEMBL5603359

Cc1c(C)n(C2([Zr](Cl)(Cl)C3(n4c(C)c(C)c5ccccc54)C=Cc4ccccc43)C=Cc3ccccc32)c2ccccc12

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MCHR2 Q969V1 1/20 0.30
MCHR1 Q99705 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600304 0.86 MCHR2 (0.33) MCHR2MCHR1
SCHEMBL5600446 0.76 SLC6A2 (0.30)
SCHEMBL5600794 0.75 CA1 (0.42) KDM4EALDH1A1
Hydrochloric Acid SCHEMBL5603362 0.75 KDM4E (0.37) KDM4EMCHR2MCHR1ALDH1A1
Hydrochloric Acid SCHEMBL5603356 0.75 KDM4E (0.34) KDM4EMCHR2MCHR1ALDH1A1
SCHEMBL5603568 0.69
SCHEMBL5604165 0.69 CDK4 (0.31)
SCHEMBL5603931 0.68
SCHEMBL5600041 0.68 OXTR (0.32)
SCHEMBL1685527 0.62 OXTR (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed