SCHEMBL5604165

SCHEMBL5604165

Cl[Zr](Cl)(C1(n2ccc3ccccc32)C=Cc2ccccc21)C1(n2ccc3ccccc32)C=Cc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31
BIRC5 O15392 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603568 0.75
SCHEMBL5600304 0.75 MCHR2 (0.33)
SCHEMBL5600446 0.74 SLC6A2 (0.30)
SCHEMBL6445115 0.74 CDK4 (0.40) CDK4CCND1
Hydrochloric Acid SCHEMBL5604171 0.72 CDK4 (0.39) CDK4CCND1
Hydrochloric Acid SCHEMBL5604161 0.72 CDK4 (0.32) CDK4CCND1
SCHEMBL5600041 0.70 OXTR (0.32)
SCHEMBL5603359 0.69 KDM4E (0.31)
SCHEMBL6064142 0.68
SCHEMBL5600794 0.65 CA1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed