SCHEMBL5603420

SCHEMBL5603420

C[Si](C)(C1=Cc2ccccc2C1Cl)C1=Cc2ccccc2C1Cl.[Zr]

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4002159 0.76 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2
SCHEMBL28743130 0.74 LMNA (0.31)
SCHEMBL27519902 0.71 LMNA (0.32) CYP19A1CYP11B1CYP11B2
SCHEMBL8335287 0.69 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2
SCHEMBL6064686 0.69 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2
SCHEMBL8577674 0.69
SCHEMBL9124724 0.69 HTR2A (0.31)
SCHEMBL216903 0.68 HTR2A (0.32)
SCHEMBL30523892 0.68 HTR2A (0.32)
SCHEMBL218230 0.68 HTR2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270602-B1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU KOSAN CO (JP) 2007-10-03 EP disclosed
US-6835788-B2 As polymerization catalyst IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-28 US disclosed
US-20030027716-A1 Catalyst for vinyl compounds and process for production of vinyl polymers IDEMITSU KOSAN CO. LTD. (JP) 2003-02-06 US disclosed
EP-1270602-A1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-02 EP disclosed