SCHEMBL8335287

SCHEMBL8335287

[Li]C1C([Si](C2=Cc3ccccc3C2[Li])([Si](C)(C)C)[Si](C)(C)C)=Cc2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4002159 0.88 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2
SCHEMBL5603420 0.69 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2
SCHEMBL5090888 0.69 LMNA (0.33) CYP19A1CYP11B1CYP11B2
SCHEMBL7642643 0.67 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
SCHEMBL27550145 0.67 MAOA (0.38) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL7525125 0.65 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL6813002 0.65 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL7536192 0.65 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL6813624 0.65 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Benzene SCHEMBL6817712 0.65 LMNA (0.31) CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0836608-B1 METALLOCENES WITH SILYL-SUBSTITUTED BRIDGES AND THEIR USE FOR OLEFIN POLYMERIZATION BOREALIS AG (AT) 1999-12-15 EP disclosed
US-5945367-A Metallocenes with silyl-substituted bridges and their use for olefin polymerization BOREALIS AG (AT) 1999-08-31 US disclosed
EP-0836608-A1 METALLOCENES WITH SILYL-SUBSTITUTED BRIDGES AND THEIR USE FOR OLEFIN POLYMERIZATION PCD-Polymere Gesellschaft m.b.H. (AT) 1998-04-22 EP disclosed
WO-1997002276-A1 METALLOCENES WITH SILYL-SUBSTITUTED BRIDGES AND THEIR USE FOR OLEFIN POLYMERIZATION PCD POLYMERE GESELLSCHAFT MBH (AT) 1997-01-23 WO disclosed