SCHEMBL5603604

SCHEMBL5603604

Cl[Hf](Cl)(C1C(n2nnc3ccccc32)=Cc2ccccc21)C1C(n2nnc3ccccc32)=Cc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
RAB9A P51151 2/20 0.39
KCNMA1 Q12791 1/20 0.39
ACHE P22303 1/20 0.35
ALDH1A1 P00352 5/20 0.35
LMNA P02545 1/20 0.35
SLC9A1 P19634 4/20 0.35
POLB P06746 2/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
KEAP1 Q14145 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
THPO P40225 1/20 0.35
CYP4Z1 Q86W10 1/20 0.35
TSHR P16473 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603229 0.78 RAB9A (0.39) SMN1; SMN2RAB9AKCNMA1ACHEALDH1A1
SCHEMBL5601936 0.78 RAB9A (0.39) SMN1; SMN2RAB9AKCNMA1ACHEALDH1A1
Hydrochloric Acid SCHEMBL5603598 0.77 RAB9A (0.43) SMN1; SMN2RAB9AKCNMA1ACHEALDH1A1
Hydrochloric Acid SCHEMBL5603220 0.77 RAB9A (0.43) SMN1; SMN2RAB9AKCNMA1ACHEALDH1A1
Hydrochloric Acid SCHEMBL5601924 0.77 RAB9A (0.43) SMN1; SMN2RAB9AKCNMA1ACHEALDH1A1
SCHEMBL5602767 0.76 MGAM (0.35) SMN1; SMN2RAB9ALMNAGAA
SCHEMBL5601306 0.76 KDM4E (0.35)
SCHEMBL5599790 0.74 KDM4E (0.36) POLBATM
SCHEMBL5602512 0.71
SCHEMBL5603439 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed