Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249828 | 0.78 | SRD5A1 (0.49) | AKR1C3SRD5A1HTR1ASIGMAR1PDPK1 | |
| SCHEMBL6249826 | 0.71 | SRD5A1 (0.44) | AKR1C3SRD5A1HTR1ASIGMAR1PDPK1 | |
| SCHEMBL7799982 | 0.70 | SRD5A1 (0.65) | SRD5A1HTR1ASIGMAR1 | |
| SCHEMBL29539187 | 0.68 | STS (0.70) | AKR1C3MAPTHTR2B | |
| SCHEMBL5677682 | 0.68 | STS (0.70) | AKR1C3MAPTHTR2B | |
| SCHEMBL10031984 | 0.68 | STS (0.70) | AKR1C3MAPTHTR2B | |
| SCHEMBL14079692 | 0.68 | STS (0.70) | AKR1C3MAPTHTR2B | |
| SCHEMBL1258196 | 0.68 | STS (0.70) | AKR1C3MAPTHTR2B | |
| SCHEMBL6249099 | 0.67 | PDPK1 (0.45) | AKR1C3SRD5A1HTR1ASIGMAR1PDPK1 | |
| SCHEMBL19924612 | 0.67 | AKR1C3 (0.39) | AKR1C3SRD5A1HTR1ASIGMAR1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007097719-A1 | CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2007-08-30 | — | — | WO | disclosed |