Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 19/20 | 0.41 |
| ▸ | RAF1 | P04049 | 18/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541536 | 0.90 | BRAF (0.43) | BRAFRAF1PLAU | |
| SCHEMBL5592994 | 0.89 | RAF1 (0.48) | BRAFRAF1 | |
| SCHEMBL4551368 | 0.85 | RAF1 (0.46) | BRAFRAF1PLAU | |
| SCHEMBL5604506 | 0.82 | PLAU (0.40) | BRAFRAF1PLAU | |
| SCHEMBL4541538 | 0.80 | RAF1 (0.56) | BRAFRAF1 | |
| SCHEMBL4544150 | 0.77 | USP30 (0.44) | BRAFRAF1PLAU | |
| SCHEMBL5623710 | 0.77 | RAF1 (0.50) | BRAFRAF1PLAU | |
| SCHEMBL4408603 | 0.75 | RAF1 (0.48) | BRAFRAF1 | |
| SCHEMBL4551369 | 0.74 | RAF1 (0.53) | BRAFRAF1 | |
| SCHEMBL5602958 | 0.74 | RAF1 (0.45) | BRAFRAF1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |