Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602313 | 0.78 | DDB1 (0.43) | DDB1CRBNALDH1A1L3MBTL1 | |
| SCHEMBL5604114 | 0.77 | NOS3 (0.32) | NOS1NOS2 | |
| SCHEMBL5601216 | 0.76 | MAPT (0.31) | MAPTHPGDNOS2 | |
| SCHEMBL5604270 | 0.74 | CYP19A1 (0.43) | DDB1CRBNCYP19A1ALDH1A1LMNA | |
| SCHEMBL5602729 | 0.73 | MAPT (0.36) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL5612680 | 0.73 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL5601130 | 0.73 | MAPT (0.39) | ALDH1A1LMNAMAPTMEN1HPGD | |
| SCHEMBL5600361 | 0.72 | MAPT (0.38) | ALDH1A1LMNAMAPTMEN1HPGD | |
| SCHEMBL5600340 | 0.72 | MAPT (0.38) | ALDH1A1LMNAMAPTMEN1HPGD | |
| SCHEMBL5602448 | 0.72 | MAPT (0.38) | ALDH1A1LMNAMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |