SCHEMBL5603984

SCHEMBL5603984

CC(CCCC12C=CC(CC1)C2)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.35
ALOX5 P09917 2/20 0.33
NR1I2 O75469 2/20 0.33
LTA4H P09960 1/20 0.33
GABRR1 P24046 2/20 0.32
CYP1A2 P05177 1/20 0.32
ACE2 Q9BYF1 1/20 0.30
TBXAS1 P24557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5073028 0.92 GABRR1 (0.33) BLMGABRR1CYP1A2
SCHEMBL4262536 0.85 ACE2 (0.31) ACE2
SCHEMBL2980437 0.82
SCHEMBL7120876 0.73
SCHEMBL20362170 0.66 OPRM1 (0.36) CYP1A2
SCHEMBL10946785 0.65
SCHEMBL20362195 0.65
SCHEMBL10759080 0.65 SMN1; SMN2 (0.47) BLMLTA4HGABRR1CYP1A2
SCHEMBL22319316 0.65
SCHEMBL4821807 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0997482-B1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO (JP) 2007-01-17 EP disclosed
US-6346581-B1 CURABLE COMPOSITION COMPRISING POLYMER OBTAINED BY INTRODUCING FUNCTIONAL GROUP INTO CYCLOOLEFIN ADDITION POLYMER CONSISTING OF UNITS DERIVED FROM CYCLOOLEFIN MONOMERS WITH AND WITHOUT SIDE CHAIN HAVING 4 OR MORE CARBONS, HARDENING AGENT NIPPON ZEON CO., LTD (JP) 2002-02-12 US disclosed
EP-0997482-A1 MODIFIED CYCLOOLEFIN ADDITION POLYMER AND CURABLE RESIN COMPOSITION CONTAINING THE SAME NIPPON ZEON CO., LTD. (JP) 2000-05-03 EP disclosed