Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650713 | 0.89 | KDM1A (0.41) | OPRM1OPRL1MAOAMAOBKDM1A | |
| SCHEMBL1978762 | 0.82 | — | — | |
| SCHEMBL30180312 | 0.81 | MEN1 (0.36) | MAOAGRIN2BMEN1KMT2AMAOB | |
| SCHEMBL443563 | 0.80 | MAOA (0.40) | OPRM1OPRL1MAOACYP3A4MAOB | |
| SCHEMBL7120876 | 0.75 | — | — | |
| SCHEMBL17912773 | 0.73 | KCNA3 (0.39) | SIGMAR1KMT2A | |
| SCHEMBL1010916 | 0.73 | POLA1 (0.31) | — | |
| SCHEMBL8372326 | 0.73 | POLA1 (0.31) | — | |
| SCHEMBL152343 | 0.73 | POLA1 (0.31) | — | |
| SCHEMBL153538 | 0.73 | POLA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565850-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | Promerus, LLC (US) | 2019-11-13 | — | — | EP | claimed |
| WO-2018129121-A1 | POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS | PROMERUS, LLC (US) | 2018-07-12 | — | — | WO | claimed |