Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602549 | 0.88 | — | — | |
| SCHEMBL5603041 | 0.78 | RECQL (0.34) | RECQLLRRK2MGAMGAASI | |
| SCHEMBL5602767 | 0.78 | MGAM (0.35) | RECQLLRRK2MGAMGAASI | |
| Hydrochloric Acid SCHEMBL5602758 | 0.77 | LRRK2 (0.36) | RECQLLRRK2MGAMGAASI | |
| Hydrochloric Acid SCHEMBL5603035 | 0.77 | LRRK2 (0.36) | RECQLLRRK2MGAMGAASI | |
| Hydrochloric Acid SCHEMBL5604106 | 0.77 | LRRK2 (0.36) | RECQLLRRK2MGAMGAASI | |
| SCHEMBL5601936 | 0.76 | RAB9A (0.39) | GAA | |
| SCHEMBL5601922 | 0.75 | BIRC5 (0.40) | MAPK8MAPK9MAPK10 | |
| SCHEMBL5602699 | 0.74 | — | — | |
| SCHEMBL5600402 | 0.73 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |