SCHEMBL5604175

SCHEMBL5604175

C[Si](C)=[Zr](C1C=Cc2ccccc21)(C1C=Cc2ccccc21)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.33
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
THPO P40225 1/20 0.31
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857144 0.76 HTR2A (0.37) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6908310 0.75 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL376490 0.75 HTR2A (0.36) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL1538971 0.73 HTR2A (0.35) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL6906177 0.72 HTR2A (0.34) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7774282 0.72 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL3386413 0.72 HTR2A (0.35) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL28670525 0.71 HTR2A (0.38) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL5084848 0.71 SLC6A2 (0.33) SLC6A2
SCHEMBL30577433 0.70 HTR2A (0.40) HTR2AKDM4ELMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3312200-B1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD MITSUI CHEMICALS INC (JP) 2019-06-19 EP disclosed
EP-3312200-A1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD Mitsui Chemicals, Inc. (JP) 2018-04-25 EP disclosed
EP-2955187-B1 SOLID POLYALUMINOXANE COMPOSITION, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2018-01-31 EP disclosed
EP-2955187-A1 SOLID POLYALUMINOXANE COMPOSITION, CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, AND METHOD FOR PRODUCING SOLID POLYALUMINOXANE COMPOSITION Mitsui Chemicals, Inc. (JP) 2015-12-16 EP disclosed
US-7160949-B2 Olefin block copolymers, processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2007-01-09 US disclosed
EP-1209179-B1 PROCESSES FOR PRODUCING POLYOLEFIN COMPOSITION MITSUI CHEMICALS INC (JP) 2005-11-02 EP disclosed
EP-1275670-B1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF MITSUI CHEMICALS INC (JP) 2005-08-10 EP disclosed
US-20030055179-A1 Olefin block copolymers processes for producing the same and uses thereof MITSUI CHEMICALS, INC. (JP) 2003-03-20 US disclosed
EP-1275670-A1 OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2003-01-15 EP disclosed
EP-1209179-A1 PROCESSES FOR PRODUCING POLYOLEFIN COMPOSITION Mitsui Chemicals, Inc. (JP) 2002-05-29 EP disclosed