SCHEMBL6906177

SCHEMBL6906177

C[Si](C)=[Zr](c1ccccc1)(c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8754746 0.90 HTR2A (0.33) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL8754873 0.82 HTR2A (0.33) HTR2AHTR6
SCHEMBL6857144 0.77 HTR2A (0.37) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL7061981 0.77 SIGMAR1 (0.34) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL8754920 0.77 HTR2A (0.30) HTR2A
SCHEMBL376490 0.76 HTR2A (0.36) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL6908310 0.76 HTR2A (0.36) HTR2ASIGMAR1KDM4ELMNATP53
SCHEMBL7066166 0.76 SIGMAR1 (0.33) HTR2ASIGMAR1KDM4ELMNATP53
Hydrochloric Acid SCHEMBL7065674 0.76 SIGMAR1 (0.33) HTR2ASIGMAR1KDM4ELMNATP53
Bromide SCHEMBL7064187 0.76 SIGMAR1 (0.33) HTR2ASIGMAR1KDM4ELMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0783022-B2 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
EP-0783022-B1 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
EP-0719803-B1 Process for the production of cycloolefin random copolymer MITSUI CHEMICALS INC (JP) 2001-03-21 EP disclosed
US-6063871-A SPECIFIC HIGH-DENSITY ETHYLENE POLYMER AND A SPECIFIC ETHYLENE POLYMER, IN WHICH AT LEAST ONE IS PREPARED USING A METALLOCENE CATALYST, AND THE DENSITY RATIO THEREBETWEEN EXCEEDS 1; MOLDABILITY, CRACK RESISTANCE, STRENGTH AND RIGIDITY MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) 2000-05-16 US disclosed
EP-0570126-B1 Method for producing graft-modified copolymers MITSUBISHI CHEM CORP (JP) 1998-09-30 EP disclosed
US-5650471-A COPOLYMERIZING AN ALPHA-OLEFIN AND A CYCLOOLEFIN IN THE PRESENCE OF A CATALYST FORMED FROM A TRANSITION METAL COMPOUND AND AN ORGANIC ALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-22 US disclosed
EP-0783022-A1 ETHYLENIC POLYMER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-09 EP disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0729983-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP disclosed
EP-0719803-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-07-03 EP disclosed
US-5334664-A Graft polymerization an unsaturated cyclic copolymer of propylene, bicycloheptene or tetracyclododecene with vinyl, vinylidene, unsaturated dicarboxylic acids or esters monomers MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1994-08-02 US disclosed
EP-0570126-A1 Method for producing graft-modified copolymers MITSUBISHI CHEMICAL CORPORATION (JP) 1993-11-18 EP disclosed