⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503958 | 0.87 | KDM4E (0.46) | — | |
| SCHEMBL5154 | 0.84 | — | — | |
| SCHEMBL27722910 | 0.82 | ALDH1A1 (0.50) | — | |
| SCHEMBL94166 | 0.79 | — | — | |
| SCHEMBL11504301 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL11503848 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL772051 | 0.76 | GLA (0.45) | — | |
| SCHEMBL469156 | 0.75 | — | — | |
| SCHEMBL16938740 | 0.75 | — | — | |
| SCHEMBL308185 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946478-B1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1688406-A2 | Polymeric resin compounds and their preparation | Aventis Pharmaceuticals Products Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1674484-A2 | Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid componds | Aventis Pharmaceuticals Products Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| CN-1238323-C | Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds | AVENTIS PHARMA INC (US) | 2006-01-25 | — | — | CN | disclosed |
| CN-1235925-C | Solid phase synthesing method of aldehyde, ketonic, oxime amine and isohydroximic acid compound | AVENTIS MEDICINE CORP (US) | 2006-01-11 | — | — | CN | disclosed |
| EP-0946478-A4 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARM PROD INC (US) | 2004-09-08 | — | — | EP | disclosed |
| CN-1500769-A | Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds | ���µ�˹ҩ�﹫˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1496999-A | Solid phase synthesing method of aldehyde, ketonic, oxime amine and isohydroximic acid compound | ���µ�˹ҩ�﹫˾ | 2004-05-19 | — | — | CN | disclosed |
| EP-0871439-B1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | AVENTIS PHARMA INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6710208-B2 | REACTING AN N-ALKYLATED POLYMERIC HYDROXAMIC ACID RESIN WITH AN ORGANOMETALLIC REAGENT TO LIBERATE THE KETONE | AVENTIS PHARMACEUTICALS INC. | 2004-03-23 | — | — | US | disclosed |
| US-20020183558-A1 | Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha, beta-unsaturated carboxylic acid and aldehyde compounds | AVENTIS PHARMACEUTICALS INC. | 2002-12-05 | — | — | US | disclosed |
| US-6392010-B1 | FLUOROPHENYL HYDROXYLAMINE RESIN | AVENTIS PHARMACEUTICALS INC. | 2002-05-21 | — | — | US | disclosed |
| US-6133409-A | REACTING A SOLID SUPPORT-BOUND N-ALKYLATED HYDROXAMIC ACID WITH A CARBON-NITROGEN CLEAVING ORGANOMETALLIC COMPUND TO LIBERATE THE PRODUCT KETONE | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-10-17 | — | — | US | disclosed |
| US-6057369-A | USE IN THE TREATMENT OF DISEASE STATES ASSOCIATED WITH PROTEINS THAT MEDIATE CELLULAR ACTIVITY WHICH ARE CAPABLE OF BEING MODULATED BY INHIBITING A MATRIX METALLOPROTEINASE (MMP), TUMOR NECROSIS FACTOR (TNF) OR CYCLIC AMP | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-05-02 | — | — | US | disclosed |
| CN-1240418-A | Solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds | RHONE POULENC RORER PHARMA (US) | 2000-01-05 | — | — | CN | disclosed |
| EP-0946478-A1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0871439-A4 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE POULENC RORER PHARMA (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0871439-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1998029376-A1 | PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-07-09 | — | — | WO | disclosed |
| WO-1997024117-A1 | SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |